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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of proliferative vitreoretinopathy (PVR)
ncRNA name TGFβ2 siRNA
ncRNA Category siRNA
Disease name proliferative vitreoretinopathy (PVR)
Species Rattus norvegicus
Tissues/Cell_line retinas and the proliferative membranes
Methods siRNA injection, ELISA, RT-PCR
Expression pattern associated
Functional description The combinatorial use of UTMD(ultrasound-targeted microbubble destruction) and rAAV2-mediated RNAi targeting TGF-β2 and PDGF-B can serve as a novel approach to attenuate PVR.
PubMed ID 22499528
Year 2012
Title A novel approach to attenuate proliferative vitreoretinopathy using ultrasound-targeted microbubble destruction and recombinant adeno-associated virus-mediated RNA interference targeting transforming growth factor-β2 and platelet-derived growth factor-B.
Drug-related ncRNA NO

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